Page 109 - Proceeding The 2nd International Seminar of Science and Technology : Accelerating Sustainable Innovation Towards Society 5.0

nd
The 2 International Seminar of Science and Technology
“Accelerating Sustainable innovation towards Society 5.0”
ISST 2022 FST UT 2022
Universitas Terbuka
mechanism i.e., the ability of bacteria to transfer plasmids containing
antibiotic resistance genes to the strains or to the bacteria of other
species [15] [11], and the ability of E. coli in biofilm formation [16].

2.2 Biofilm

Figure 2. Composition of biofilm (a) and biofilm formation (b) [17].

Biofilm is a group of microbes that live in the matrix secretions of
extracellular polymeric substance (EPS) or exopolysaccharides. EPS
is a biopolymer which usually has size 10-30 nm and thickness around
0.2 – 1µm. 5-35% of the biofilm’s volume is microbe and the rest is
matrix. This matrix generally consists of ~1% DNA, ~1% RNA, 1-60%
structural proteins, 1-40% lipids, enzymes, 40-95% extracellular
polysaccharides, also 2-35% microbes which consist of bacterial cells
on the surface of microecosystems that is initiate biofilm formation
(cells of the microenvironmental layer) and dormant persister or

88 ISST 2022 – FST Universitas Terbuka, Indonesia
International Seminar of Science and Technology “Accelerating Sustainable
Towards Society 5.0