Page 335 - Proceeding The 2nd International Seminar of Science and Technology : Accelerating Sustainable Innovation Towards Society 5.0
P. 335

nd
               The 2  International Seminar of Science and Technology
               “Accelerating Sustainable innovation towards Society 5.0”
               ISST 2022 FST UT 2022
               Universitas Terbuka
               furokhromone,  glycerol,  linolenic  acid,  myristic  acid,  nootkatone,
               starch, saponins, sesquiterpenes, sitosterol, stearic acid, terpenoids,
               polyphenols, and valence [6] also contains compounds of quercetin,
               kaempferol, tannins, glycosides, gallic acid and p-coumarin acid [7]
               and  cinema  [10]  Phytochemical  compounds  in  M.pudica  include
               glycosides, mimosine [4] tannins, flavonoids, steroids, terpenoids and
               sterols  [9]  alkaloids,  quinine,  phenols,  saponins,  and  coumarins  [5]
               triterpenes,  quinines,  c-glycosylflavones,  phenols,  and  polyphenols
               [11].
               Various studies have proven the activity of C.rotundus and M.pudica
               extracts  on  various  types  of  bacteria.  C.rotundus  extract  has
               antibacterial  effect  against  Staphylococcus  aureus,  Bacillus  subtilis
               [6],  [12]  Staphylococcus  epidermidis  [13]  and  Propionibacterium
               Acnes  [7]  Enterococcus  aureus,  Escherichia  coli,  Pseudomonas
               aeruginosa [2],[15] Shigella dysenteriae, Salmonella typhimurium, and
               Pseudomonas  aeroginosa  Shigella  dysenteriae  [6].  While  M.pudica
               extract affects Staphylococcus aureus, Staphylococcus epidermidis,
               Streptococcus  agalactiae  [8],  [11],  Bacillus  subtilis  [5],[16],[17]  also
               affects Escherichia coli, Klebsiella pneumoniaea, Pseudomonas spp.,
               Klebsiella   pneumonia,   Proteus   vulgaris   [8],   Pseudomonas
               aeroginosa,  Salmonella  sp.,  Shigella  flexineri  [18]  and  Salmonella
               typhi [5],[16],[17]. The ability of herbs as antibacterial becomes the
               basis  for  using  them  in  various  dosage  forms,  to  prevent  the
               transmission  of  bacteria  to  humans.  Pathogenic  bacteria  such  as
               Staphylococcus  aureus  (S.aureus),  Staphylococcus  epidermidis
               (S.epidermidis),  Escherichia  coli  (E.coli),  Pseudomonas  aeruginosa
               (P.aeruginosa),  and  Salmonella  typhi  (S.typhi),  can  be  transmitted
               through the mediation of hand skin, feces, contaminated equipment
               [19], [20], [21]. Efforts to prevent bacterial transmission are by applying
               hand washing using soap [8] or antiseptic [21]. Antiseptics are used to
               inhibit  bacterial  colonization  and  prevent  bacterial  transmission
               through the skin of the hands [21].
               Preparations  of  antibacterial  drugs  that  also  function  as  antiseptics
               can  be  obtained  from  a  combination  of  several  plant  extracts.  The


               ISST 2022 – FST Universitas Terbuka, Indonesia            303
               International Seminar of Science and Technology “Accelerating Sustainable
               Towards Society 5.0
   330   331   332   333   334   335   336   337   338   339   340