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nd
                                  he 2  International Seminar of Science and Technology
                                   “Accelerating Sustainable innovation towards Society 5.0”
                                                       ISST 2022 FST UT 2022
                                                          Universitas Terbuka

          pudica  against  S.epidermidis,  S.aureus,  E.coli,  and  P.aeruginosa,
          except for S.typhi produced an effect equivalent to 70% alcohol, and
          the phenol coefficient value was close to 5% phenol. In conclusion,
          the  combined  activity  of  C.rotundus  and  M.pudica  infusion  on  the
          number of tested bacterial colonies and from the value of the phenol
          coefficient can be developed as an alternative antiseptic.
          Keywords:  antibacterial  activity,  Cyperus  rotundus,  Mimosa  pudica,
          phenol coefficient value, number of bacterial colonies.
          1  INTRODUCTION
          Weed plant Java grass or Cyperus rotundus (C.rotundus) and the shy
          princess  or  Mimosa  pudica  (M.pudica)  are  widely  found  in  the
          mainland region of Indonesia.  Cyperus rotundus  is a type of grass
          Family-Cyperaceae [1],[2],[3] and Mimosa pudica belongs to the family
          Mimosoideaee  [4],  [5]  These  two  types  of  plants  as  been  used
          empirically  by  several  circles  of  society  herbs  to  treat  various
          diseases.  Traditionally  C.rotundus  can  be  used  to  treat  infections
          gastrointestinal  tract,  dyspepsia,  diarrhea,  dysentery,  ascites,
          vomiting, cholera, fever [2] wounds, ulcers, and abrasions [1], [6] also
          for  urinary  stones,  nail  inflammation,  nausea,  and  vomiting  [7].
          Pharmacological  and  biological  activity  C.rotundus  is  anti-
          inflammatory,   antidiabetic,   antidiarrheal,   cytoprotective,
          antimutagenic, antimicrobial, antibacterial, antioxidant, cytotoxic, and
          apoptotic [6] as well as a sedative, antipyretic, analgesic, and wound
          healing [1],[2].
          The  M.pudica  plant  has  been  used  as  a  medicine  for  urogenital
          disorders, piles, dysentery, and sinus, and can be applied to wounds
          [8] as an anti-infective tract, respiratory infections, herpes, diarrhea,
          asthma, insomnia, skin infections, and swelling due to wounds [4]. The
          pharmacological  effects  of  M.pudica  are  antivenom,  antifertility,
          anticonvulsant,  antidepressant,  aphrodisiac,  antibacterial  [4],
          antihepatotoxic,   antioxidant,   diuretic,   anti-inflammatory,   and
          antimicrobial  (antibacterial,  antiviral)  [9].  The  bioactive  content  in
          these two plants is as efficacious as an antibacterial. The rhizome of
          C.rotundus  contains  flavonoids,  alkaloids,  cyperol,  fatty  oils,

          302                          ISST 2022 – FST Universitas Terbuka, Indonesia
                    International Seminar of Science and Technology “Accelerating Sustainable
                                                         Towards Society 5.0
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