Page 118 - Proceeding The 2nd International Seminar of Science and Technology : Accelerating Sustainable Innovation Towards Society 5.0

nd
The 2 International Seminar of Science and Technology
“Accelerating Sustainable innovation towards Society 5.0”
ISST 2022 FST UT 2022
Universitas Terbuka
3 CONCLUSIONS
From the discussion above, it can be concluded that bacteriophages
are considered to have potential as antibiofilm agents for E. coli
because it has several advantages over antibiotics which are
bacteriophage is natural predators of bacteria that is specific, do not
affected by the ability of bacterial resistance, has ability to produce
enzymes that degrade biofilm and infect bacteria in it and can infect
persister or dormant bacteria. These are based on the studies by
Bumunang et al., [46] which reported that bacteriophages can reduce
the formation of E. coli biofilm by 2.5 and 2.1 log10 CFU/cm2;
Gonzales-Gomez et al., [47] that reported, bacteriophage can reduce
E. coli biofilm by 0.95 log10 CFU/mL - 6.70 log10 CFU/mL; and Triana
[48] that showed, E. coli antibiofilm activity on prevention, inhibition,
and degradation activities about 50-150%.

ISST 2022 – FST Universitas Terbuka, Indonesia 97
International Seminar of Science and Technology “Accelerating Sustainable
Towards Society 5.0